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Neil Desai Selected Research

Albumin-Bound Paclitaxel

7/2010nab-Paclitaxel in patients with advanced solid tumors and hepatic dysfunction: a pilot study.
5/2009SPARC Expression Correlates with Tumor Response to Albumin-Bound Paclitaxel in Head and Neck Cancer Patients.
5/2008Protein nanoparticles as drug carriers in clinical medicine.
7/2006Influence of formulation vehicle on metronomic taxane chemotherapy: albumin-bound versus cremophor EL-based paclitaxel.
2/2006Increased antitumor activity, intratumor paclitaxel concentrations, and endothelial cell transport of cremophor-free, albumin-bound paclitaxel, ABI-007, compared with cremophor-based paclitaxel.
11/2005Phase I and pharmacokinetics trial of ABI-007, a novel nanoparticle formulation of paclitaxel in patients with advanced nonhematologic malignancies.
11/2005Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with breast cancer.
9/2005Multicenter phase II trial of ABI-007, an albumin-bound paclitaxel, in women with metastatic breast cancer.
6/2005Comparative preclinical and clinical pharmacokinetics of a cremophor-free, nanoparticle albumin-bound paclitaxel (ABI-007) and paclitaxel formulated in Cremophor (Taxol).
5/2002Phase I and pharmacokinetic study of ABI-007, a Cremophor-free, protein-stabilized, nanoparticle formulation of paclitaxel.

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Neil Desai Research Topics

Disease

19Neoplasms (Cancer)
11/2021 - 06/2005
12Prostatic Neoplasms (Prostate Cancer)
04/2024 - 07/2006
6Neoplasm Metastasis (Metastasis)
11/2021 - 06/2008
6Breast Neoplasms (Breast Cancer)
04/2011 - 09/2005
4Neutropenia
07/2010 - 09/2005
4Hypersensitivity (Allergy)
05/2008 - 05/2002
3Renal Cell Carcinoma (Grawitz Tumor)
09/2021 - 01/2017
3Ovarian Neoplasms (Ovarian Cancer)
02/2009 - 11/2005
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
09/2023
1Penile Neoplasms (Penile Cancer)
09/2023
1Acute Kidney Injury (Acute Renal Failure)
11/2022
1Heart Failure
11/2022
1Urinary Bladder Neoplasms (Bladder Cancer)
11/2021
1Wounds and Injuries (Trauma)
08/2021
1Hypoglycemia (Reactive Hypoglycemia)
07/2021
1Lymphoma (Lymphomas)
04/2021
1Non-Hodgkin Lymphoma (Lymphosarcoma)
04/2021
1Hemolytic-Uremic Syndrome
10/2020
1Diarrhea
10/2020
1Brain Neoplasms (Brain Tumor)
10/2019
1Lymphopenia (Lymphocytopenia)
12/2018
1Mycosis Fungoides
12/2018
1Thrombocytopenia (Thrombopenia)
10/2013
1Hypophosphatemia
10/2013
1Pancreatic Neoplasms (Pancreatic Cancer)
12/2011
1Adenocarcinoma
12/2011
1Fatigue
07/2010
1Hyperbilirubinemia
07/2010
1Multiple Myeloma
04/2010
1Head and Neck Neoplasms (Head and Neck Cancer)
05/2009
1Carcinoma (Carcinomatosis)
02/2009
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
05/2008
1Melanoma (Melanoma, Malignant)
05/2008
1Thrombosis (Thrombus)
04/2007
1Cardiovascular Diseases (Cardiovascular Disease)
04/2007
1Febrile Neutropenia
09/2005

Drug/Important Bio-Agent (IBA)

11Paclitaxel (Taxol)FDA LinkGeneric
04/2011 - 06/2005
10Albumin-Bound PaclitaxelFDA Link
07/2010 - 05/2002
7AlbuminsIBA
10/2013 - 11/2005
7130-nm albumin-bound paclitaxelIBA
12/2011 - 05/2008
4Proteins (Proteins, Gene)FDA Link
04/2011 - 11/2005
4SolventsIBA
06/2008 - 11/2005
3Sirolimus (Rapamycin)FDA Link
10/2013 - 05/2008
2AndrogensIBA
10/2023 - 01/2017
2CreatinineIBA
11/2022 - 10/2020
2GemcitabineFDA Link
12/2018 - 12/2011
2Prostate-Specific Antigen (Semenogelase)IBA
04/2018 - 01/2017
2Aspartate Aminotransferases (Aspartate Transaminase)IBA
10/2013 - 07/2010
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
04/2011 - 06/2008
2LuciferasesIBA
04/2011 - 06/2008
2Bevacizumab (Avastin)FDA Link
04/2011 - 06/2008
2Cysteine (L-Cysteine)FDA Link
02/2009 - 11/2005
2Castor Oil (Oil, Castor)IBA
11/2005 - 11/2005
1Oxygen (Dioxygen)IBA
11/2022
1insulin receptor-related receptor (IRR)IBA
11/2021
1Complement System Proteins (Complement)IBA
11/2021
1DNA (Deoxyribonucleic Acid)IBA
11/2021
1Clonidine (ST 155)FDA LinkGeneric
07/2021
1Asparaginase (Elspar)FDA Link
04/2021
1pembrolizumabIBA
04/2021
1Immune Checkpoint InhibitorsIBA
04/2021
1SodiumIBA
10/2020
1Alemtuzumab (Campath)FDA Link
12/2018
110-propargyl-10-deazaaminopterinFDA Link
12/2018
1acivicin (AT 125)IBA
10/2013
1perifosineIBA
04/2010
1MTOR InhibitorsIBA
04/2010
1TOR Serine-Threonine KinasesIBA
04/2010
1Phosphatidylinositols (Phosphatidylinositol)IBA
04/2010
1Biomarkers (Surrogate Marker)IBA
02/2009
1Messenger RNA (mRNA)IBA
02/2009
1Docetaxel (Taxotere)FDA Link
05/2008
1Antineoplastic Agents (Antineoplastics)IBA
05/2008
1Cytotoxins (Cytolysins)IBA
05/2008
1Taxoids (Taxanes)IBA
05/2008
1omega-Chloroacetophenone (Mace)IBA
04/2007
1cremophorIBA
02/2006
1Albumin ReceptorsIBA
11/2005
1Carrier Proteins (Binding Protein)IBA
11/2005
1AcidsIBA
11/2005
1cremophor ELIBA
05/2002

Therapy/Procedure

11Radiotherapy
04/2024 - 01/2017
11Therapeutics
10/2023 - 04/2007
4Premedication
11/2005 - 05/2002
3Castration
10/2023 - 01/2021
2Intensity-Modulated Radiotherapy (Radiotherapy, Intensity Modulated)
01/2024 - 04/2018
2Prostatectomy (Retropubic Prostatectomy)
01/2019 - 01/2017
1Organ Sparing Treatments
09/2023
1Brachytherapy
09/2023
1Cardiopulmonary Bypass (Heart-Lung Bypass)
11/2022
1Cystectomy
11/2021
1Length of Stay
08/2021
1Immunotherapy
04/2021
1Renal Replacement Therapy (Therapies, Renal Replacement)
10/2020
1Image-Guided Radiotherapy
04/2018
1Adjuvant Radiotherapy
01/2017
1Re-Irradiation
01/2017
1Stents
04/2007
1Intravenous Infusions
11/2005